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1

Breakage and drying behaviour of granules in a continuous fluid bed dryer: Influence of process parameters and wet granule transfer

De Leersnyder, F., Vanhoorne, V., Bekaert, H., Vercruysse, J., Ghijs, M., Bostijn, N., Verstraeten, M., Cappuyns, P., Van Assche, I., Vander Heyden, Y., Ziemons, E., Remon, J.P., Nopens, I., Vervaet,

Journal:

European Journal of Pharmaceutical Sciences

Year:

2018

Language:

english

File:

PDF, 1.38 MB

english, 2018

2

Robust statistics in data analysis — A review: Basic concepts

M. Daszykowski, K. Kaczmarek, Y. Vander Heyden, B. Walczak

Journal:

Chemometrics and Intelligent Laboratory Systems

Year:

2007

Language:

english

File:

PDF, 639 KB

english, 2007

3

Experimental designs and their recent advances in set-up, data interpretation, and analytical applications

Bieke Dejaegher, Yvan Vander Heyden

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2011

Language:

english

File:

PDF, 1.93 MB

english, 2011

4

HPTLC methods to assay active ingredients in pharmaceutical formulations: A review of the method development and validation steps

D.H. Shewiyo, E. Kaale, P.G. Risha, B. Dejaegher, J. Smeyers-Verbeke, Y. Vander Heyden

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2012

Language:

english

File:

PDF, 793 KB

english, 2012

5

The Epa Mask and Ceremony

Marsha Vander Heyden

Journal:

Year:

1977

Language:

english

File:

PDF, 7.68 MB

english, 1977

6

Reappraisal of Hypothesis Testing for Method Validation: Detection of Systematic Error by Comparing the Means of Two Methods or of Two Laboratories

Hartmann, Christa., Smeyers-Verbeke, Johanna., Penninckx, Wim., Vander Heyden, Yvan., Vankeerberghen, Pieter., Massart, Desire L.

Journal:

Analytical Chemistry

Year:

1995

Language:

english

File:

PDF, 981 KB

english, 1995

7

A review on the application of chromatographic methods, coupled to chemometrics, for food authentication (Chromatography-chemometrics in food authentication)

Esteki, M., Simal-Gandara, J., Shahsavari, Z., Zandbaaf, S., Dashtaki, E., Vander Heyden, Yvan

Journal:

Year:

2018

Language:

english

File:

PDF, 596 KB

english, 2018

8

HILIC methods in pharmaceutical analysis

Bieke Dejaegher, Yvan Vander Heyden

Journal:

Journal of Separation Science

Year:

2010

Language:

english

File:

PDF, 301 KB

english, 2010

9

Automatic program for peak detection and deconvolution of multi-overlapped chromatographic signals: Part I: Peak detection

G. Vivó-Truyols, J.R. Torres-Lapasió, A.M. van Nederkassel, Y. Vander Heyden, D.L. Massart

Journal:

Journal of Chromatography A

Year:

2005

Language:

english

File:

PDF, 709 KB

english, 2005

10

Robustness tests on the United States Pharmacopoeia XXVI HPLC assay for ginsenosides in Asian and American ginseng using an experimental design

Yong-Guo Li, Hong Liu, Y. Vander Heyden, Ming Chen, Zheng-Tao Wang, Zhi-Bi Hu

Journal:

Analytica Chimica Acta

Year:

2005

Language:

english

File:

PDF, 264 KB

english, 2005

11

Boosted regression trees, multivariate adaptive regression splines and their two-step combinations with multiple linear regression or partial least squares to predict blood–brain barrier passage: A case study

E. Deconinck, M.H. Zhang, F. Petitet, E. Dubus, I. Ijjaali, D. Coomans, Y. Vander Heyden

Journal:

Analytica Chimica Acta

Year:

2008

Language:

english

File:

PDF, 1.40 MB

english, 2008

12

Modelling the quality of enantiomeric separations based on molecular descriptors

S. Caetano, Y. Vander Heyden

Journal:

Chemometrics and Intelligent Laboratory Systems

Year:

2006

Language:

english

File:

PDF, 537 KB

english, 2006

13

Automatic program for peak detection and deconvolution of multi-overlapped chromatographic signals: Part II: Peak model and deconvolution algorithms

G. Vivó-Truyols, J.R. Torres-Lapasió, A.M. van Nederkassel, Y. Vander Heyden, D.L. Massart

Journal:

Journal of Chromatography A

Year:

2005

Language:

english

File:

PDF, 298 KB

english, 2005

14

Lawsone accumulation in normal and transformed cultures of henna, Lawsonia inermis

A. T. Bakkali, M. Jaziri, A. Foriers, Y. Vander Heyden, M. Vanhaelen, J. Homès

Journal:

Plant Cell, Tissue and Organ Culture

Year:

1997

Language:

english

File:

PDF, 466 KB

english, 1997

15

Influence of putrescine, cadaverine, spermidine or spermine on the formation of N-nitrosamine in heated cured pork meat

G. Drabik-Markiewicz, B. Dejaegher, E. De Mey, T. Kowalska, H. Paelinck, Y. Vander Heyden

Journal:

Year:

2011

Language:

english

File:

PDF, 1.01 MB

english, 2011

16

The variance of screening and supersaturated design results as a measure for method robustness

B. Dejaegher, J. Smeyers-Verbeke, Y. Vander Heyden

Journal:

Analytica Chimica Acta

Year:

2005

Language:

english

File:

PDF, 167 KB

english, 2005

17

Randomization tests to identify significant effects in experimental designs for robustness testing

B. Dejaegher, X. Capron, J. Smeyers-Verbeke, Y. Vander Heyden

Journal:

Analytica Chimica Acta

Year:

2006

Language:

english

File:

PDF, 291 KB

english, 2006

18

Drug impurity profiling: Method optimization on dissimilar chromatographic systems: Part I: pH optimization of the aqueous phase

M. Dumarey, R. Sneyers, W. Janssens, I. Somers, Y. Vander Heyden

Journal:

Analytica Chimica Acta

Year:

2009

Language:

english

File:

PDF, 617 KB

english, 2009

19

A performance comparison of modern statistical techniques for molecular descriptor selection and retention prediction in chromatographic QSRR studies

Tim Hancock, Raf Put, Danny Coomans, Yvan Vander Heyden, Yvette Everingham

Journal:

Chemometrics and Intelligent Laboratory Systems

Year:

2005

Language:

english

File:

PDF, 474 KB

english, 2005

20

Development of a Ginkgo biloba fingerprint chromatogram with UV and evaporative light scattering detection and optimization of the evaporative light scattering detector operating conditions

A.M. van Nederkassel, V. Vijverman, D.L. Massart, Y. Vander Heyden

Journal:

Journal of Chromatography A

Year:

2005

Language:

english

File:

PDF, 418 KB

english, 2005

21

Pretreatments of chromatographic fingerprints for quality control of herbal medicines

Cheng-Jian Xu, Yi-Zeng Liang, Foo-Tim Chau, Yvan Vander Heyden

Journal:

Journal of Chromatography A

Year:

2006

Language:

english

File:

PDF, 546 KB

english, 2006

22

Ruggedness and robustness testing

Bieke Dejaegher, Yvan Vander Heyden

Journal:

Journal of Chromatography A

Year:

2007

Language:

english

File:

PDF, 515 KB

english, 2007

23

Robust partial least squares model for prediction of green tea antioxidant capacity from chromatograms

M. Daszykowski, Y. Vander Heyden, B. Walczak

Journal:

Journal of Chromatography A

Year:

2007

Language:

english

File:

PDF, 451 KB

english, 2007

24

Automated alignment of one-dimensional chromatographic fingerprints

M. Daszykowski, Y. Vander Heyden, C. Boucon, B. Walczak

Journal:

Journal of Chromatography A

Year:

2010

Language:

english

File:

PDF, 397 KB

english, 2010

25

Classification of drugs in absorption classes using the classification and regression trees (CART) methodology

E. Deconinck, T. Hancock, D. Coomans, D.L. Massart, Y. Vander Heyden

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2005

Language:

english

File:

PDF, 236 KB

english, 2005

26

Stationary phases in the screening of drug/impurity profiles and in their separation method development: Identification of columns with different and similar selectivities

E. Van Gyseghem, M. Jimidar, R. Sneyers, M. De Smet, E. Verhoeven, Y. Vander Heyden

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2006

Language:

english

File:

PDF, 670 KB

english, 2006

27

Isotopic ratios to detect infringements of patents or proprietary processes of pharmaceuticals: Two case studies

E. Deconinck, A.M. van Nederkassel, I. Stanimirova, M. Daszykowski, F. Bensaid, M. Lees, G.J. Martin, J.R. Desmurs, J. Smeyers-Verbeke, Y. Vander Heyden

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2008

Language:

english

File:

PDF, 2.20 MB

english, 2008

28

Raman spectroscopy as a process analytical technology (PAT) tool for the in-line monitoring and understanding of a powder blending process

T.R.M. De Beer, C. Bodson, B. Dejaegher, B. Walczak, P. Vercruysse, A. Burggraeve, A. Lemos, L. Delattre, Y. Vander Heyden, J.P. Remon, C. Vervaet, W.R.G. Baeyens

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2008

Language:

english

File:

PDF, 907 KB

english, 2008

29

Polyphenols isolated from antiradical extracts of Mallotus metcalfianus

Céline Rivière, Van Nguyen Thi Hong, Luc Pieters, Bieke Dejaegher, Yvan Vander Heyden, Minh Chau Van, Joëlle Quetin-Leclercq

Journal:

Year:

2009

Language:

english

File:

PDF, 233 KB

english, 2009

30

Influence of the sequence of experiments in a ruggedness test when drift occurs

Y. Vander Heyden, A. Bourgeois, D.L. Massart

Journal:

Analytica Chimica Acta

Year:

1997

Language:

english

File:

PDF, 1.14 MB

english, 1997

31

Guidance for robustness/ruggedness tests in method validation

Y Vander Heyden, A Nijhuis, J Smeyers-Verbeke, B.G.M Vandeginste, D.L Massart

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2001

Language:

english

File:

PDF, 259 KB

english, 2001

32

Supersaturated designs: set-ups, data interpretation, and analytical applications

B. Dejaegher, Y. Vander Heyden

Journal:

Analytical and Bioanalytical Chemistry

Year:

2008

Language:

english

File:

PDF, 276 KB

english, 2008

33

Ruggedness tests for a high-performance liquid Chromatographic assay: Comparison of an evaluation at two and three levels by using two-level Plackett-Burman designs

Y.Vander Heyden, C. Hartmann, D.L. Massart, L. Michel, P. Kiechle, F. Erni

Journal:

Analytica Chimica Acta

Year:

1995

Language:

english

File:

PDF, 824 KB

english, 1995

34

Evaluation of the influence of proline, hydroxyproline or pyrrolidine in the presence of sodium nitrite on N-nitrosamine formation when heating cured meat

G. Drabik-Markiewicz, B. Dejaegher, E. De Mey, S. Impens, T. Kowalska, H. Paelinck, Y. Vander Heyden

Journal:

Analytica Chimica Acta

Year:

2010

Language:

english

File:

PDF, 1.63 MB

english, 2010

35

Chromatographic separation techniques and data handling methods for herbal fingerprints: A review

Christophe Tistaert, Bieke Dejaegher, Yvan Vander Heyden

Journal:

Analytica Chimica Acta

Year:

2011

Language:

english

File:

PDF, 822 KB

english, 2011

36

Evaluation of dissolution profiles using principal component analysis

E. Adams, R. De Maesschalck, B. De Spiegeleer, Y. Vander Heyden, J. Smeyers-Verbeke, D.L. Massart

Journal:

International Journal of Pharmaceutics

Year:

2001

Language:

english

File:

PDF, 205 KB

english, 2001

37

10.1038/47100

Dowdy, Steven F., Vocero-Akbani, Adita M., Heyden, Nancy Vander, Lissy, Natalie A., Ratner, Lee

Journal:

Year:

1999

Language:

english

File:

PDF, 126 KB

english, 1999

38

10.1038/47105

Dowdy, Steven F., Vocero-Akbani, Adita M., Heyden, Nancy Vander, Lissy, Natalie A., Ratner, Lee

Journal:

Year:

1999

Language:

english

File:

PDF, 120 KB

english, 1999

39

10.1038/47120

Dowdy, Steven F., Vocero-Akbani, Adita M., Heyden, Nancy Vander, Lissy, Natalie A., Ratner, Lee

Journal:

Year:

1999

Language:

english

File:

PDF, 159 KB

english, 1999

40

10.1038/47126

Dowdy, Steven F., Vocero-Akbani, Adita M., Heyden, Nancy Vander, Lissy, Natalie A., Ratner, Lee

Journal:

Year:

1999

Language:

english

File:

PDF, 207 KB

english, 1999

41

10.1038/47109

Dowdy, Steven F., Vocero-Akbani, Adita M., Heyden, Nancy Vander, Lissy, Natalie A., Ratner, Lee

Journal:

Year:

1999

Language:

english

File:

PDF, 116 KB

english, 1999

42

10.1038/47114

Dowdy, Steven F., Vocero-Akbani, Adita M., Heyden, Nancy Vander, Lissy, Natalie A., Ratner, Lee

Journal:

Year:

1999

Language:

english

File:

PDF, 214 KB

english, 1999

43

10.1038/47123

Dowdy, Steven F., Vocero-Akbani, Adita M., Heyden, Nancy Vander, Lissy, Natalie A., Ratner, Lee

Journal:

Year:

1999

Language:

english

File:

PDF, 148 KB

english, 1999

44

Review on modelling aspects in reversed-phase liquid chromatographic quantitative structure–retention relationships

R. Put, Y. Vander Heyden

Journal:

Analytica Chimica Acta

Year:

2007

Language:

english

File:

PDF, 347 KB

english, 2007

45

Evaluation of Artemisia annua infusion efficacy for the treatment of malaria in Plasmodium chabaudi chabaudi infected mice

Magnus A. Atemnkeng, Bantuzeko Chimanuka, Bieke Dejaegher, Yvan Vander Heyden, Jacqueline Plaizier-Vercammen

Journal:

Experimental Parasitology

Year:

2009

Language:

english

File:

PDF, 199 KB

english, 2009

46

Statistical Confidence for Variable Selection in QSAR Models via Monte Carlo Cross-Validation

Konovalov, Dmitry A., Sim, Nigel, Deconinck, Eric, Vander Heyden, Yvan, Coomans, Danny

Journal:

Journal of Chemical Information and Modeling

Year:

2008

Language:

english

File:

PDF, 616 KB

english, 2008

47

Development of a fluid bed granulation process control strategy based on real-time process and product measurements

Burggraeve, Anneleen, Silva, Ana F.T., Van Den Kerkhof, Tom, Hellings, Mario, Vervaet, Chris, Paul Remon, Jean, Vander Heyden, Yvan, De Beer, Thomas

Journal:

Year:

2012

Language:

english

File:

PDF, 745 KB

english, 2012

48

Robust Cross-Validation of Linear Regression QSAR Models

Konovalov, Dmitry A., Llewellyn, Lyndon E., Vander Heyden, Yvan, Coomans, Danny

Journal:

Journal of Chemical Information and Modeling

Year:

2008

Language:

english

File:

PDF, 504 KB

english, 2008

49

Prediction of Peptide Retention at Different HPLC Conditions from Multiple Linear Regression Models

Ba̧czek, Tomasz, Wiczling, Paweł, Marszałł, Michał, Heyden, Yvan Vander, Kaliszan, Roman

Journal:

Journal of Proteome Research

Year:

2005

Language:

english

File:

PDF, 269 KB

english, 2005

50

The occurrence of N-nitrosamines, residual nitrite and biogenic amines in commercial dry fermented sausages and evaluation of their occasional relation

De Mey, Eveline, De Klerck, Katrijn, De Maere, Hannelore, Dewulf, Lore, Derdelinckx, Guy, Peeters, Marie-Christine, Fraeye, Ilse, Vander Heyden, Yvan, Paelinck, Hubert

Journal:

Year:

2014

Language:

english

File:

PDF, 591 KB

english, 2014

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